Publication de Nicole Delepine : Expanding prostheses in long term results in limb salvage surgery in children.

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Publié sur : European Society of Surgical Oncology - 2001
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Expanding prostheses in long term results in limb salvage surgery in children.
G. Delepine, F. Delepine, H. Cornille, S. Alkallaf, Nicole Delepine

Expanding prostheses in long term results in limb salvage surgery in children.



Introduction :


Conservative surgery for young children with bone sarcoma of lower limb remains a challenge. In 1985 we proposed an expandable prosthesis and present here our long-term results.

Patients :


50 p. (26 males and 24 females aged 4-28 years) with tumors of the limbs were treated by our team between 1984 and 1999. Histology was mostly osteosarcoma (35) and Ewing (10). Locations were distal femur in 36, upper tibia in 5 total femur in 5 and proximal femur in 4. 33 were first hand p. (20 with localized disease and 2 already metastatic) en bloc resection. The 17 other p. were referred to us after induction therapy, with progressive disease, metastasis (3) or local recurrence (1).

Method :


In 16 p. the expanding prosthesis was inserted immediately after the resection, in 8 during the following year and for the 26 other p. later to treat a length discrepancy. 107 sequences of lengthening have been performed in 40 p.

Results :


7 patients died from illness. 42 other are disease free survivors with a median follow up of 91 months (maximal 192 - minimal 6). Half (22) of the patients are adults. The average lengthening is 4.07 centimeters (minimal 0.5 - maximal 12). 23 of the patients had to be re-operated for complications. Deep infection occurred in 10 patients (20 %) resulting in amputation for 3 of them. According to EMSOS criteria the functional result is excellent in 16, good in 18, fair in 11 and poor in 5.

Conclusion :


Long term results of lengthening prostheses confirm that this procedure is an excellent alternative to amputation and permit to keep a functional limb in nearly 90% of patients. The most severe complication is deep infection underlining the interest of last generations of grower with minimally invasive lengthening.




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